KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
35.45
Human Site:
S318
Identified Species:
65
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
S318
L
P
E
V
E
N
L
S
K
R
Y
E
E
I
Y
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
S465
L
P
E
V
E
N
L
S
K
R
Y
E
E
I
Y
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
S318
L
P
E
V
E
S
L
S
K
R
Y
E
E
I
Y
Dog
Lupus familis
XP_534118
897
103170
S287
L
P
E
V
E
S
L
S
R
Q
Y
E
E
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
S312
L
P
E
V
E
S
L
S
K
R
Y
E
E
V
Y
Rat
Rattus norvegicus
P33568
920
105007
S311
L
P
E
L
E
S
L
S
K
R
Y
E
E
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
S308
L
P
E
V
E
N
L
S
K
Q
Y
E
K
I
Y
Chicken
Gallus gallus
Q90600
921
104417
S308
L
P
E
V
D
V
L
S
K
Q
Y
D
E
L
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
S304
L
P
P
M
E
A
L
S
K
Q
Y
E
E
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
N303
D
G
N
S
K
A
I
N
R
V
Y
E
Q
H
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
L177
L
I
A
K
G
S
M
L
S
E
C
S
E
L
V
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
L347
L
Q
S
S
L
N
I
L
E
K
D
Y
D
D
A
Maize
Zea mays
Q3LXA7
1010
111475
K325
L
L
Q
G
D
S
L
K
P
S
L
I
I
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
93.3
80
N.A.
86.6
80
N.A.
86.6
66.6
N.A.
66.6
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
86.6
N.A.
N.A.
46.6
N.A.
33.3
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
16
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
16
0
0
0
0
0
8
8
8
8
0
% D
% Glu:
0
0
62
0
62
0
0
0
8
8
0
70
70
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
16
0
0
0
0
8
8
39
0
% I
% Lys:
0
0
0
8
8
0
0
8
62
8
0
0
8
0
0
% K
% Leu:
93
8
0
8
8
0
77
16
0
0
8
0
0
31
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
31
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
70
8
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
31
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
16
39
0
0
0
0
0
% R
% Ser:
0
0
8
16
0
47
0
70
8
8
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
54
0
8
0
0
0
8
0
0
0
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
77
8
0
0
70
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _